Eptifibatide mo Togafitiga o Acute Coronary Syndrome 188627-80-7
Fa'amatalaga Oloa
| Igoa | Eptifibatide |
| Numera CAS | 188627-80-7 |
| fua mole | C35H49N11O9S2 |
| mamafa mole | 831.96 |
| EINECS Numera | 641-366-7 |
| Malosi | 1.60±0.1 g/cm3(Va'ai) |
| Tulaga teuina | Fa'amau i le mago, teu i le pusaaisa, i lalo ole -15°C |
Synonyms
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6-(Aminoimi nomethyl) -N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDEBRIDGE,MPA1-CYS6).
Platelet Glycoprotein Antagonist
Etifibatide (integrilin) o se mea fou polypeptide platelet glycoprotein IIb/IIIa receptor antagonist, lea e taofia ai platelet aggregation ma thrombosis e ala i le taofia o le auala masani mulimuli o platelet aggregation. Pe a faʻatusatusa i le monoclonal antibody abciximab, eptifibatide e sili atu le malosi, sili atu le faʻatonuga ma faʻapitoa faʻapipiʻi i le GPIIb / IIIa ona o le i ai o se tasi o le amino acid substitution-lysine e sui ai arginine. O le mea lea, e tatau ona i ai se togafitiga lelei i le togafitiga faʻalavelave o le maʻi o le coronary syndrome. Platelet glycoprotein IIb/IIIa receptor antagonist drugs ua atiaʻe tele, ma o loʻo i ai nei 3 ituaiga o sauniuniga e mafai ona faʻaaogaina i falemaʻi faavaomalo, abciximab, eptifibatide ma tirofiban. ). E itiiti le poto masani i le faʻaaogaina o le platelet glycoprotein GPIIb/IIIa antagonists talitali i Saina, ma o vailaʻau o loʻo maua e matua faʻatapulaʻaina. E na o le tasi le vailaʻau, tirofiban hydrochloride, o loʻo i luga o le maketi. O le mea lea, na fausia ai se platelet glycoprotein IIb fou. /IIIa fa'afeagai talitali e taua tele. O le eptifibatide i totonu o le atunuʻu o se oloa faʻatusa na gaosia e Chengdu Sino Biological Products Co., Ltd.
Fa'avasegaga
Fa'avasegaga o vaila'au fa'aputuga fa'aantiplatelet
Antiplatelet aggregation drugs e mafai ona vaevaeina i ni vaega se tolu: 1. Cyclooxygenase-1 (COX-1) inhibitors, pei ole aspirin. 2. Taofi le platelet aggregation fa'aosoina e le adenosine diphosphate (ADP), e pei o le clopidogrel, prasugrel, cangrelor, ticagrelor, ma isi. vaega o vaila'au ma mea'ai aoga mai vaila'au fa'aSaina.
