Oloa
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Givosiran
Givosiran API o se RNA fa'alavelave fa'alavelave fa'apipi'i (siRNA) su'esu'eina mo le togafitia o le porphyria acute hepatic (AHP). E fa'atatau tonu i leALAS1gene (aminolevulinic acid synthase 1), lea e aofia i le ala o le biosynthesis heme. E fa'aogaina e le au su'esu'e Givosiran e su'esu'e ai le RNA interference (RNAi) -fa'avae togafitiga, ate fa'atatau i le silencing, ma le fa'avasegaina o ala fa'ato'aga o lo'o a'afia i le porphyria ma fa'afitauli tau kenera.
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Pegcetacoplan
Pegcetacoplan o se pegylated cyclic peptide e galue e pei o le C3 complement inhibitor, ua atiaʻe mo le togafitia o faʻamaʻi faʻapipiʻiina e pei o le paroxysmal nocturnal hemoglobinuria (PNH) ma le geographic atrophy (GA) i le macular degeneration tausaga.
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Plozasiran
O le Plozasiran API o se RNA fa'alavelave laiti (siRNA) fa'atupuina mo le togafitia o le hypertriglyceridemia ma fa'afitauli cardiovascular ma metabolic. E fa'atatau i leAPOC3gene, lea e faʻapipiʻiina apolipoprotein C-III, o se faʻatonuga autu o le metabolism triglyceride. I suʻesuʻega, o loʻo faʻaaogaina Plozasiran e suʻesuʻe ai le RNAi-based lipid-lowering strategy, gene-silencing specificity, ma togafitiga umi mo tulaga e pei ole family chylomicronemia syndrome (FCS) ma fefiloi dyslipidemia.
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Zilebesiran
Zilebesiran API o se su'esu'ega laiti fa'alavelave RNA (siRNA) na atia'e mo togafitiga o le toto maualuga. E fa'atatau i leAGTgene, lea e fa'ailoga angiotensinogen-o se vaega autu o le renin-angiotensin-aldosterone system (RAAS). I suʻesuʻega, o loʻo faʻaaogaina Zilebesiran e suʻesuʻe ai le faʻaogaina o auala mo le faʻatonutonuina o le toto maualuga, RNAi tekinolosi tuʻuina atu, ma le lautele lautele o le ala RAAS i faʻamaʻi cardiovascular ma fatugaʻo.
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Palopegteriparatide
O le Palopegteriparatide o se agonist o le hormone receptor agonist ua leva ona galue (PTH1R agonist), na fausia mo togafitiga o le hypoparathyroidism masani. O se analog pegylated o le PTH (1-34) ua mamanuina e tuʻuina atu ai le faʻatonuina o le calcium faʻatasi ma le tuʻuina i vaiaso taʻitasi.
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GHRP-6
GHRP-6 (Growth Hormone Releasing Peptide-6) o se hexapeptide synthetic lea e galue o se secretagogue hormone tuputupu aʻe, faʻaosofia le tuʻuina atu masani o le hormone tuputupu aʻe (GH) e ala i le faʻagaoioia o le GHSR-1a receptor.
API Features:
Mama ≥99%
Gaosi e ala ile fa'ameamea ole peptide synthesis (SPPS)
Tuuina atu mo le R&D ma fa'aoga fa'apisinisi
GHRP-6 o se peptide suʻesuʻega faʻapitoa mo le lagolago metabolic, toe faʻafouina maso, ma le faʻaogaina o hormonal.
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GHRP-2
GHRP-2 (Growth Hormone Releasing Peptide-2) o se hexapeptide faʻapipiʻi ma le malosi o le tuputupu aʻe o le hormone secretagogue, ua fuafuaina e faʻaosofia ai le tuʻuina atu masani o le hormone tuputupu aʻe (GH) e ala i le faʻagaoioia o le GHSR-1a receptor i le hypothalamus ma le pituitary.
API Features:
Mama ≥99%
Avanoa mo R&D ma sapalai fa'apisinisi, fa'atasi ai ma fa'amaumauga QC atoa
GHRP-2 o se peptide suʻesuʻega taua i matāʻupu o endocrinology, faʻafouga faʻafomaʻi, ma togafitiga faʻatausaga.
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Hexarelin
O le Hexarelin o se peptide secretagogue peptide (GHS) tuputupu ae malosi ma malosi GHSR-1a agonist, na atiina ae e faaosofia ai le faʻamalolo o le hormone tupu (GH). E a'afia i le aiga ghrelin mimetic ma e aofia ai le ono amino acids (se hexapeptide), e ofoina atu le faʻaleleia atili o le metabolic ma le malosi o le tuʻuina atu o le GH pe a faʻatusatusa i analogs muamua e pei o le GHRP-6.
API Features:
Mama ≥ 99%
Fa'atupuina e ala ile fa'aogaina ole peptide fa'amautu (SPPS)
GMP-pei o tulaga, maualalo endotoxin ma solvent toega
Sapalai fetuutuunai: R&D i le fua faapisinisi
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Melanotan II
API Features:
maualuga mama ≥ 99%
Fa'apipi'iina e ala i le fa'aogaina o le peptide fa'ama'oti (SPPS)
E maualalo le endotoxin, maualalo le soli o totoe
E maua ile R&D ile fua faapisinisi -
Melanotan 1
Melanotan 1 API o lo'o gaosia i le fa'aogaina o le fa'aogaina o le peptide synthesis (SPPS) fa'atekonolosi i lalo ole GMP-pei o le pulea lelei o tulaga lelei.
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maualuga mama ≥99%
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Fa'atosina-vaega peptide fa'aogaina (SPPS)
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GMP-pei o le gaosiga tulaga
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Faʻamaumauga atoa: COA, MSDS, faʻamaumauga mautu
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Sapalai fa'ateleina: Su'esu'ega i tulaga fa'apisinisi
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MOTS-C
MOTS-C API o loʻo gaosia i lalo ole GMP-pei o tuʻutuʻuga e faʻaogaina ai le faʻaogaina o le peptide synthesis (SPPS) faʻatekonolosi e faʻamautinoa ai lona tulaga maualuga, maualuga le mama ma maualuga le mautu mo suʻesuʻega ma togafitiga faʻaoga.
Mea e Fa'atau:Mama ≥ 99% (faʻamaonia e HPLC ma LC-MS),
E maualalo le endotoxin ma mea o totoe o le solvent,
Tuuina atu e tusa ai ma ICH Q7 ma GMP-pei o tulafono,
E mafai ona ausia le gaosiga tele, mai le milligram-level R&D batches i le kalama ma le kilokalama-level sapalai pisinisi. -
Ipamorelin
Ipamorelin API o loʻo saunia e ala i le tulaga maualuga ** faʻasologa o le peptide synthesis process (SPPS) ** ma faia le faʻamamaina maʻoti ma suʻega lelei, talafeagai mo le faʻaogaina vave o paipa i suʻesuʻega faasaienisi ma atinaʻe ma kamupani vailaʻau.
O vaega o oloa e aofia ai:
Mama ≥99% (Su'ega HPLC)
Leai se endotoxin, maualalo le soli o totoe, maualalo ion uamea faaleagaina
Tuuina atu se seti atoa o pepa lelei: COA, lipoti o suʻesuʻega mautu, suʻesuʻega o alaleo le mama, ma isi.
Tuuina atu tulaga kalama-tulaga-kilo-kilo