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Atosiban Acetate Used for Anti Premature Birth Featured Image
  • Atosiban Acetate Used for Anti Premature Birth
  • Atosiban Acetate Used for Anti Premature Birth

Atosiban Acetate Fa'aaogaina mo le Fanau Mai Fa'ataoto

Fa'amatalaga Puupuu:

Igoa: Atosiban

Numera CAS: 90779-69-4

fua mole: C43H67N11O12S2

mamafa mole: 994.19

Numera EINECS: 806-815-5

Mea fa'apuna: 1469.0±65.0 °C (Va'ai)

Malosi: 1.254±0.06 g/cm3(Va'ai)

Tulaga teuina: -20°C

Soluble: H2O: ≤100 mg/mL


Fa'amatalaga Oloa

Faailoga o oloa

Fa'amatalaga Oloa

Igoa Atosiban
Numera CAS 90779-69-4
fua mole C43H67N11O12S2
mamafa mole 994.19
EINECS Numera 806-815-5
Fa'apuna 1469.0±65.0 °C (Va'ai)
Malosi 1.254±0.06 g/cm3(Va'ai)
Tulaga teuina -20°C
Solubility H2O: ≤100 mg/mL

Fa'amatalaga

Atosiban acetate o se polypeptide cyclic cyclic disulfide e aofia ai 9 amino acids.O se mole oxytocin ua suia i tulaga 1, 2, 4 ma le 8. O le N-terminus o le peptide o le 3-mercaptopropionic acid (thiol ma O le sulfhydryl group of [Cys]6 o loʻo fausia ai se faʻamauga disulfide), o le C-terminal o le. i le tulaga o se amide, o le amino acid lona lua i le N-terminal o se ethylated ua suia [D-Tyr(Et)]2, ma o le atosiban acetate o loʻo faʻaaogaina i vailaʻau e pei o le vineka O loʻo i ai i le tulaga o se masima masima, masani. lauiloa o le atosiban acetate.

Fa'atatauga

Atosiban o se oxytocin ma vasopressin V1A tu'ufa'atasi tali fa'afeagai, o le oxytocin receptor e fa'atusa fa'atusa ma le vasopressin V1A talitali.Pe a poloka le oxytocin receptor, e mafai lava e le oxytocin ona galue e ala i le V1A receptor, o lea e tatau ai ona poloka auala e lua o loʻo i luga i le taimi e tasi, ma o se faʻalavelave e tasi o le tasi faʻafeiloaʻi e mafai ona taofia lelei le faʻamaʻiina o le uterine.O se tasi foi lea o mafuaʻaga autu e le mafai ai e le β-receptor agonists, calcium channel blockers ma le prostaglandin synthase inhibitors ona faʻamalosia lelei le faʻalavelaveina o le uterine.

Aafiaga

Atosiban o se tuʻufaʻatasiga faʻafesoʻotaʻi o le oxytocin ma le vasopressin V1A, o lona fausaga vailaʻau e tutusa ma le lua, ma e maualuga lona vavalalata mo tali, ma tauva ma oxytocin ma vasopressin V1A faʻafeiloaʻi, ma poloka ai le ala gaioiga o le oxytocin ma vasopressin ma faʻaitiitia. fa'atosina o le manava.

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