Pegcetacoplan

Pegcetacoplan API

Pegcetacoplan o se pegylated cyclic peptide e galue e pei o le C3 complement inhibitor, ua atiaʻe mo le togafitia o faʻamaʻi faʻapipiʻiina e pei o le paroxysmal nocturnal hemoglobinuria (PNH) ma le geographic atrophy (GA) i le macular degeneration tausaga.

Mechanism & Research:
Pegcetacoplan e fusifusia e faʻapipiʻi le protein C3 ma le C3b, e taofia ai le faʻagaoioia o le faʻamaʻi faʻapipiʻi. E fa'aitiitia ai:
Hemolysis ma le mumu ile PNH
Fa'aleagaina sela o le retina ile atrophy fa'afanua
Manu'a a'ano o lo'o fa'asalaina i isi fa'alavelave fa'atosina